The loss of DNA polymerase epsilon accessory subunits POLE3-POLE4 leads to BRCA1-independent PARP inhibitor sensitivity
Selected by
14 November 2023
Audrey Noireterre
Lincrnas enable germ cells differentiation by promoting PUF proteins condensation
Selected by
30 October 2023
Umutcan Kaan Bozan et al.
Tardigrades dramatically upregulate DNA repair pathway genes in response to ionizing radiation
Selected by
18 October 2023
Isabella Cisneros
Glutamate helps unmask the differences in driving forces for phase separation versus clustering of FET family proteins in sub-saturated solutions
Selected by
03 October 2023
Erich Sohn
CRISPR-dependent base editing screens identify separation of function mutants of RADX with altered RAD51 regulatory activity
Selected by
06 September 2023
Jessica Chevallier, Pierre Caron
Proteasome condensate formation is driven by multivalent interactions with shuttle factors and K48-linked ubiquitin chains
Selected by
05 September 2023
Aniruddha Das
H2O2 sulfenylates CHE linking local infection to establishment of systemic acquired resistance
Selected by
23 August 2023
Marc Somssich
Conserved cardiolipin-mitochondrial ADP/ATP carrier interactions assume distinct structural and functional roles that are clinically relevant
Selected by
14 July 2023
Barbora Knotkova
Discovery and Validation of Context-Dependent Synthetic Mammalian Promoters
Selected by
21 June 2023
Jessica L. Teo
Caveola mechanotransduction reinforces the cortical cytoskeleton to promote epithelial resilience
Selected by
15 June 2023
Teodora Piskova
Polθ is phosphorylated by Polo-like kinase 1 (PLK1) to enable repair of DNA double strand breaks in mitosis
Selected by
05 June 2023
Pierre Caron
Biologically informed NeuralODEs for genome-wide regulatory dynamics
Selected by
31 May 2023
Benjamin Dominik Maier